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Microorganism accumulation and growth onboard a spacecraft may impact adversely on crew efficiency and safety as well as system, subsystems and payload. The results of test campaigns performed at Alenia Spazio in Summer 1993 are reported here. From them, some simple and effective prevention methods to be applied during the manufacturing and integration phases of a pressurised spacecraft have been identified and are here discussed. Although data obtained from Earth experience may be considered useful, it is uncertain and unfit for space station operational lifespan. Therefore, it is necessary to build a model of the phenomenon, able to provide a series of quantitative data as a function of different parameters related to environmental characteristics, crew, and on-board activities.

A Human Factors Engineering (HFE) analysis has been involved in the design process of the Mini Pressurized Logistics Module (MPLM) for the International Space Station (ISS) since the beginning, as an integrated part of the design support activities. The support of HFE in the configuration process has been directed towards the optimization of the MPLM design through the analysis and evaluation of all the interfaces occurring in the module - nominal and non-nominal - between the crew, the system and the subsystem equipment. In order to identify and analyze all the crew interfaces occurring inside the module, a systematic approach, involving different disciplines, is necessary. The integration of three different tools such as computer simulation, task analysis and mock-up test activities has been employed as an organic unit, in order to establish a comprehensive collection of useful data.