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The Montreal Protocol phase-out of chlorofluorocarbons (CFCs) has led manufacturers to develop refrigeration and air-conditioning systems that use refrigerants that do not damage stratospheric ozone. Most refrigeration industries have adapted their designs to use hydrochlorofluorocarbon (HCFC) or hydrofluorocarbon (HFC) refrigerants; new automobile air-conditioning systems use HFC-134a. These industries are now being affected by scientific investigations of greenhouse warming and questions about the effects of refrigerants on global warming. Automobile air-conditioning has three separate impacts on global warming; 1) the effects of refrigerant inadvertently released to the atmosphere from accidents, servicing, and leakage; 2) the efficiency of the cooling equipment (due to the emission of CO2 from burning fuel to power the system); and 3) the emission of CO2 from burning fuel to transport the system.