Immersion, Hyperoxia, Hypercapnia: Additive Effect Upon Pulmonary Function 941261
In a study of 6 men aged 29 to 48 we studied the effect of water body immersion during air or pure oxygen, or oxygen - 4 % CO2 gas mixture breathing upon pulmonary volumes and respiratory biomechanics (using bodyplethysmography), the extent of lung hydration (two-frequency impedansometry), and pulmonary metabolic function (by determination of the concentration of biologically active substances in the condensate of the exhaled air). We found an additive nature of immersion/hyperoxic effects upon the respiratory and metabolic pulmonary functions manifested in an acceleration and growth of a deficit in pulmonary vital capacity, a bronchoconstriction effect, increase of a lung hydration, and decrease of serotonin catabolism. Contrary to our expectation, we did non find any potentiation of oxygen induced toxic effects upon the lungs during immersion/hyperoxia/hypercapnia exposures.
Citation: Tikhonov, M., Baranov, V., and Kotov, A., "Immersion, Hyperoxia, Hypercapnia: Additive Effect Upon Pulmonary Function," SAE Technical Paper 941261, 1994, https://doi.org/10.4271/941261. Download Citation
Author(s):
Michail A. Tikhonov, Victor M. Baranov, Alexander N. Kotov
Affiliated:
Institute of Biomedical Problem
Pages: 4
Event:
International Conference On Environmental Systems
ISSN:
0148-7191
e-ISSN:
2688-3627
Also in:
SAE 1994 Transactions: Journal of Aerospace-V103-1
Related Topics:
Oxygen
Gases
Biomechanics
Water
Vehicle acceleration
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