Kinematics Response of the PMHS Brain to Rotational Loading of the Head: Development of Experimental Methods and Analysis of Preliminary Data 2018-01-0547

Experimentally derived brain response envelopes are needed to evaluate and validate existing finite element (FE) head models. Motion of the brain relative to the skull during rotational input was measured using high-speed biplane x-ray. To generate repeatable, reproducible, and scalable data, methods were developed to reduce experimental variance. An “extreme-energy” device was developed to provide a controlled input that is unaffected by specimen characteristics. Additionally, a stereotactic frame was used to deploy radiopaque markers at specific, pre-determined locations within the brain. One post-mortem human surrogate (PMHS) head specimen was subjected to repeat tests of a half-sine rotational speed pulse in the sagittal plane. The desired pulse had a peak angular speed of 40 rad/s and duration of 30 ms. Relative motion of the brain was quantified using radiopaque targets and high-speed biplane x-ray. Frontal and occipital intracranial pressure (ICP) were also measured.