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Fatigue life prediction formula proposed by Fatemi-Socie has been implemented into the fatigue analysis software - ENDURE to account for the multiaxial, out-of-phase fatigue loading conditions. Shear strain amplitude on the maximum shear strain amplitude plane and the maximum stress normal to this plane are the parameters governing such fatigue damage. This approach is compatible with the Coffin-Manson law and can be easily incorporated with the uniaxial fatigue data and finite element stress analysis to perform multiaxial fatigue life predictions. The predicted lives show good agreements with the experimental results of thin-walled tubular and notched shaft specimens of Inconel 718 and 1045-HR steel.