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The Space Station Temperature and Humidity Control Condensing Heat Exchangers will be utilized to collect and remove atmospheric water vapor generated by the metabolic and hygienic activity of crew members. The porous hydrophilic coating within the heat exchangers will always be wet. Cabin air will continuously flow through the heat exchangers during system operation which makes them a potential site for microbial colonization. This paper summarizes the findings from an ongoing study which evaluates biofilm formation on wet hydrophilic coated panels compared to panels to which microbial control measures have been applied. The control measures evaluated are an antimicrobial agent within the coating and periodic drying.