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Diffuse axonal injury (DAI) is the most frequent type of closed head injury involved in vehicular accidents, and is characterized by structural and functional damage of nerve fibers in the white matter that may be caused by their overstretch. Because nerve fibers in the white matter have an undulated network-like structure embedded in the neuroglia and extracellular matrix, and are expected to be much stiffer than other components, the strain in the nerve fiber is not necessarily equal to that in the white matter. In this study, the authors have measured strain of the nerve fibers running in various directions in porcine brain tissue subjected to uniaxial stretch and compared them with global strain (tissue strain). The nerve fiber strain had a close correlation with their direction, and was smaller than surrounding global strain.

Typical automotive related abdominal injuries occur due to contact with the rim of the steering wheel, seatbelt and armrest, however, the rate is less than in other body regions. When solid abdominal organs, such as the liver, kidneys and spleen are involved, the injury severity tends to be higher. Although sled and pendulum impact tests have been conducted using cadavers and animals, the mechanical properties and the tissue level injury tolerance of abdominal solid organs are not well characterized. These data are needed in the development of computer models, the improvement of current anthropometric test devices and the enhancement of our understanding of abdominal injury mechanisms. In this study, a series of experimental tests on solid abdominal organs was conducted using porcine liver, kidney and spleen specimens. Additionally, the injury tolerance of the solid organs was deduced from the experimental data.

Lower extremity injuries in frontal automotive crashes usually occur with footwell intrusion where both the knee and foot are constrained. In order to identify factors associated with tibial shaft injury, a series of numerical simulations were conducted using a finite element model of the whole human body. These simulations demonstrated that tibial mid-shaft injuries in frontal crashes could be caused by an abrupt change in velocity and a high rate of footwell intrusion.

A finite element model of the human lower extremity has been developed to predict lower extremity injuries in full frontal and offset frontal impact. The model included 30bones from femur to toes. Each bone was modeled using crushable solid elements for the orbicular bone and damageable shell elements for the cortical bone. The models of the long bones for the lower extremities were validated against data obtained from quasi-static 3-pointbending tests by Yamada (1970). The ankle, knee and hip joints were modeled as bone-to-bone contacts and included major ligaments and tendons. The ankle model was validated against data obtained from quasi-staticdorsiflexion, inversion and eversion tests by Petit et al. (1996) and against data obtained from dynamic impactcadaveric tests by Kitagawa et al. (1998). The possibility of using this model to predict injuries was discussed.