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Statistical process control (SPC) has been extensively used in many different industries including automotive, electronics, and aerospace, among others. SPC tools such as control charts, process capability analysis, sampling inspection, etc., have definitive and powerful impact on quality control and improvement for mass production and similar production systems. In aerospace manufacturing, however, applications of SPC tools are more challenging, especially when these tools are implemented in processes producing products of large sizes with slower production rates. For instance, following a widely accepted rule-of-thumb, about 100 units of products are required in the first phase of implementing a Shewhart type control chart. Once established, it then can be used for process control in the second phase for actual production process monitoring and control.