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Nowadays, an automotive DI Diesel engine is demanded to provide an adequate power output together with limit-complying NOx and soot emissions so that the development of a specific combustion concept is the result of a trade-off between conflicting objectives. In other words, the development of a low-emission DI diesel combustion concept could be mathematically represented as a multi-objective optimization problem. In recent years, genetic algorithm and CFD simulations were successfully applied to this kind of problem. However, combining GA optimization with actual CFD-3D combustion simulations can be too onerous since a large number of simulations is usually required, resulting in a high computational cost and, thus, limiting the suitability of this method for industrial processes.